I once had a set of roommates that had this annoying habit. If they found something funny or otherwise entertaining, they would laugh for a few moments and then declare that they "almost peed [their] pants! Really!"
I think this bothered me mostly because hello, we are adults now and it is unnecessary and undistinguished to talk about pee. It annoyed me in the same way the whole "I just threw up a little in my mouth" thing annoyed me for a few years there where Everyone was saying it All The Time.
That being said, this McSweeney's List caught me so offguard that, well, you know. The rapidfire hilarity of the seventh and eighth entries is what really got me. And you know, I read these lists for the exact reason that I expect them to be funny. Somehow that one just really hit the right spot for me. Thank you, Eric Feezell.